Background: Burn injury is often a devastating event with long-term physical andpsychosocial effects. It can result in multiple psychological sequelae.Aim: The aim ofthe current study was to investigate the relationship between self-efficacy andpsychological status among hospitalized burned patients.Subject and Methods :theresearch design A descriptive correlation design was adopted in the current study.Setting: The study was carried out in burn units at Port-Said general hospital, PortSaid, Egypt. Convenient sample of 92 adult burned patients were recruited toparticipate in this study. Two tools are used for data collection were: the DepressionAnxiety Stress Scale (DASS) and General Self-Efficacy Scale (GSE),Result: Theresults of the current study revealed that Psychological impairment was found to besever and more than half of studied patients at the anxiety, depression and stress. SelfEfficacy was low in about half of burned patients. There were negative correlationbetween Self-Efficacy and depression and stress but positive correlation withanxiety.Conclusion The study was concluded that there is a significant relationbetween stress as well as depression and anatomical site of burn, especially in theupper limb. As well as there was a significant relation found between General SelfEfficacy and patient's age. Recommendations: The importance of early psychologicalintervention to reduce the complications to recognize and treat pre-existingimpairments to reduce the complications of long-term remedy.