HEALTH RELATED QUALITY OF LIFE AND IT'S ASSOCIATION WITH MEDICATION ADHERENCE FOR PATIENTS WITH PULMONARY TUBERCULOSIS

Omar, Mohamed Mohamed; Bakr, Amal; Sobeh, Dina Al-tabay; Shehab, Mariam Sabry

doi:10.21608/pssjn.2020.33756.1034

HEALTH RELATED QUALITY OF LIFE AND IT'S ASSOCIATION WITH MEDICATION ADHERENCE FOR PATIENTS WITH PULMONARY TUBERCULOSIS

Document Type : Original Article

Authors

¹ Demonstrator of Medical Surgical Nursing Faculty of Nursing - Port Said University

² Medical Surgical Nursing, Faculty of Nursing - Port Said University

10.21608/pssjn.2020.33756.1034

Abstract

Background:Tuberculosis (TB) has been ranked to be one of the top ten causes of global mortality worldwide. The concept of health-related quality of life (HRQOL) might be of a multi-dimensional nature, it includes psychological, physical and social aspects. The effectiveness of medical interventions is influenced by adherence. Aim: This study aims to assess the correlation between health related quality of life (HRQOL) and medication adherence for Patients with pulmonary tuberculosis. Subjects and Method: A design based on descriptive correlational research was utilized. Convenient sample of pulmonary tuberculosis patients (56) at Almasaha Albahary at Port Said City and Chest Hospital at Damietta City. Three structured interviews were utilized to gather the required data. Data collection tools: Tool I: structured interviewing questionnaire, Tool II: Health Related Quality of life for patients with chronic illness, Tool III: Morisky Medication Adherence Scale (MMAS-8). Results: this study showed that 67.9% of the subjects were high psychological domain of health related quality of life and moreover, 75% of them were highly adhered to medications. Conclusion: it can conclude that three fifth of the studied patients had high QOL and three quarters of the patients had high adherence to medication. This study showed that there was statistically positive correlation between HRQOL domains (Physical, psychological, social) of HRQOL and drug adherence. Recommendation: the study recommended the event of program for patients with TB to enhance the patients’ knowledge, care management and modify their wrong beliefs associated with TB.

Keywords

References

Aggarwal, A. N., Gupta, D., Janmeja, A. K. & Jindal, S. K. (2013). Assessment of health-related quality of life in patients with pulmonary tuberculosis under program conditions. Int J Tuberc Lung Dis, 17, 947-53.

Agh, T., Domotor, P., Bartfai, Z., Inotai, A., Fujsz, E., Meszaros, A. (2015). Relationship between Medication Adherence and Health-Related Quality of Life in Subjects with COPD: A Systematic Review. Respiratory Care, 60.

Ahmad, N., Javaid, A., Syed, S.A., Basit, A., Afridi, A. K., Jaber A., et al. (2016). Effects of multidrug-resistant tuberculosis treatment on Patients’ Health Related Quality of Life: Results from a follow Up study. PlosOne, 11(7). e0159560.

Atif, M., Sulaiman, S. A., Shafie, A. A., Asif, M., Sarfraz, M. K., Low, H. C. & Babar, Z. U.( 2014). Impact of tuberculosis treatment on health-related quality of life of pulmonary tuberculosis patients: a follow-up study. Health Qual Life Outcomes, 12, 19.

Bauer, M., Ahmed, S., Benedetti, A., Greenaway, C., Lalli, M., Leavens, A., Menzies, D., Vadeboncoeur, C., Vissandjee, B., Wynne, A. &Schwartzman, K. (2015). Health-Related Quality Of Life and Tuberculosis: A Longitudinal Cohort Study. Health Qual Life Outcomes, 13, 65.

Brown, J., Capocci, S., Smith, C., Morris, S., Abubakar, I. & Lipman, M. (2015). Health status and quality of life in tuberculosis. Int J Infect Dis, 32, 68-75.

Darvishpoor Kakhki, A. & Masjedi, M. R. (2015). Factors Associated with Health-Related Quality of Life in Tuberculosis Patients Referred to the National Research Institute of Tuberculosis and Lung Disease in Tehran. Tuberc Respir Dis (Seoul), 78, 309-14.

Dujaili, J. A., Sulaiman, S. A. S., Hassali, M. A., Awaisu, A., Blebil, A. Q., & Bredle, J. M. (2015). Health-related quality of life as a predictor of tuberculosis treatment outcomes in Iraq. International Journal of Infectious Diseases, 31, 4–8.

Gounder, P. P., Harris, T. G., Anger, H., Trieu, L., Meissner, J. S., Cadwell, B. L., Ahuja, S. D. (2015). Risk for tuberculosis disease among contacts with prior positive tuberculin skin test: A Retrospective Cohort Study, New York City. Journal of General Internal Medicine, 30(6), 742–748

Hawrot, H. (2019). Pulmonary tuberculosis. Diagnostic Histopathology, 25(11), 460-462.‏

Hayward, S., Harding, R. M., McShane, H., & Tanner, R. (2018). Factors influencing the higher incidence of tuberculosis among migrants and ethnic minorities in the UK. F1000Research, 7, 461.

Hosseini, M., Shakerimoghaddam, A., Ghazalibina, M., & Khaledi, A. (2020). Aspergillus coinfection among patients with pulmonary tuberculosis in Asia and Africa countries; a systematic review and meta-analysis of cross-sectional studies. Microbial Pathogenesis, 141, 104018.

Jaber, A. A., Khan, A. H., Syed Sulaiman, S. A., Ahmad, N. & Anaam, M. S. (2016). Evaluation of Health-Related Quality of Life among Tuberculosis Patients in Two Cities in Yemen. PLoS One, 11, e0156258.

Jaber, A., & Ibrahim, B. (2019). Health-related quality of life of patients with multidrug-resistant tuberculosis in Yemen: prospective study. Health and quality of life outcomes, 17(1), 142.

Karimi, P.N., Guantai ,A. ,N., Kigondu ,C., Ogaro, T. (2017) Risk Factors For pulmonary Tuberculosis and the Effect Of chemotherapy On the Quality Of Life Of infected Patients In Nairobi city County, Kenya. Pharmaceutical Journal of Kenya Vol. 23, (1); 56-60.

Kastien-Hilka, T., Abulfathi, A., Rosenkranz, B., Bennett, B., Schwenkglenks, M., and Sinanovic, E. (2016). Health-related quality of life and its association with medication adherence in active pulmonary tuberculosis- a systematic review of global literature with focus on South Africa. Health Qual Life Outcomes 14, 42

King, C. R., & Hinds, P. S. (2003). Quality of life: From nursing and patient perspectives: theory, research, practice. Sudbury, Mass: Jones and Bartlett Publishers.

Kirenga, B.J., Ssengooba, W., Muwonge, C., Nakiyingi, L. Kyaligonza, S., Kasozi,S., Mugabe, F., Boeree, M., Joloba, M., & Okwera, A. (2015).Tuberculosis risk factors among tuberculosis patients in Kampala, Uganda: implications for tuberculosis control. BMC Public Health, 15, 13

Kodati, R., Tadepalli, A., & Chandana Reddy (2019). Pulmonary tuberculosis presenting as diffuse cystic lung disease: an atypical manifestation. Indian Journal of Tuberculosis.

Krasniqi, S., Jakupi, A., Daci, A., Tigani, B., Jupolli-Krasniqi, N., Pira, M., Neziri, B. (2017). Tuberculosis Treatment Adherence of Patients in Kosovo. Tuberculosis Research and Treatment, 2017, 1–8.

Lam, W. Y. & Fresco, P. (2015). Medication Adherence Measures: An Overview. Biomed Res Int, 2015, 217047.

Louw, J. S., Mabaso, M. & Peltzer, K. (2016). Change in Health-Related Quality of Life among Pulmonary Tuberculosis Patients at Primary Health Care Settings in South Africa: A Prospective Cohort Study. PLoS One, 11, e0151892.

Malik, M., Nasir, R., & Hussain, A. (2018). Health Related Quality of Life among TB Patients: Question Mark on Performance of TB DOTS in Pakistan. Journal of Tropical Medicine, 2018, 1–7.

Morisky, D. E., Ang, A., Krousel-Wood, M., Ward, H.J. (2008a). Predictive Validation of a Medication Adherence Measure in an Outpatient Setting. The Journal of Clinical Hypertension, 10, 348-354.

Mukherjee, P., Karmakar, P.R., Basu, R, & Lahiri, S.K. (2015). Sociodemographic and clinical profile of multi-drug resistant tuberculosis patients: A study at drug resistant tuberculosis centers of Kolkata. IOSR Journal of Dental and Medical Sciences, 14, 8, 52-58.

Theron, G., Peter, J., Zijenah, L., Chanda, D., Mangu, C., Clowes, P., Rachow, A., Lesosky, M., Hoelscher, M., Pym, A., Mwaba, P., Mason, P., Naidoo, P., Pooran, A., Sohn, H., Pai, M., Stein, D. J. & Dheda, K. (2015). Psychological distress and its relationship with non-adherence to TB treatment: a multicenter study. BMC Infect Dis, 15, 253.

Tola, H.H., Tol, A., Shojaeizadeh, D., Maroudi, G. G. (2015). Tuberculosis treatment non -adherence and lost to follow up among TB Patients with or without HIV in developing countries: A Systematic Review. Iran J Public Health, 44, (1).1 -11.

Wolters Kluwer (2015). Management of latent tuberculosis infection: An evidence-based approach. Lung India. 2015 32(3): 205-207.