STRESS, ANXIETY AND DEPRESSION AMONG ADOLESCENTS SUFFERING FROM THALASSEMIA

Document Type : Original Article

Authors

1 psychiatric nursing and mental health, faculty of nursing, port said, Egypt

2 Assist Prof. of Psychiatric Nursing and Mental Health, Faculty of Nursing - Port Said University

3 Pediatric Hematology/ Oncology and Bone Marrow Transplantation Unit- Mansoura Research Center for Cord Stem Cells, Faculty of Medicine- Mansoura University

4 lecturer in Psychiatric Nursing and Mental Health Department, Faculty of Nursing- Port Said University

Abstract

Background: Thalassemia a serious, life-limiting disease that can be life-threatening and cause great disruption in all dimensions of life. Aim: This study aimed to evaluate stress, anxiety and depression in adolescents with thalassemia. Subjects and Method: Design: A descriptive research design was utilized. Setting: Pediatric Hospital in Mansoura University and an inpatient department of El- Tadamon Hospital in Port-Said city. Subjects: The studied subjects consisted of 112 adolescents whom selected from above mentioned settings. Tools:  Data were collected through Depression Anxiety Stress Scale (DASS21), in addition to personal and clinical data questionnaire. Results: The study revealed that, approximately half of the studied adolescents (48.2%) had extremely severe level of stress, more than half of them (54.5%) had extremely severe level of anxiety, and less than one quarter of them (23.2%) had extremely severe level of depression. Conclusion: Adolescents suffering from thalassemia are exposed to multiple health problems especially what related to psychological and emotional dimensions represented in severe anxiety and stress. Recommendations: The main recommendation was designing and applying continuous educational programs for adolescents with thalassemia regarding their disease to maintain compliance to the therapeutic regimen and prevent negative impacts of thalassemia on their psychological status. These programs should be led by health professionals.
 

Keywords

Main Subjects


Ali, A., Ahmed, A., Sharaf, A., Kawakami, N., Abdeldayem, S. & Green, J. (2017). The Arabic version of the depression anxiety stress scale-21: Cumulative scaling and discriminant-validation testing. Asian Journal of Psychiatry, 1 (30), 56–58.
Boonchooduang, N., Louthrenoo, O., Choeyprasert,W., & Charoenkwan, P. (2015). Health-related quality of life in adolescents with thalassemia. Pediatric Hematology and Oncology, 32 (5), 341–348.
Caocci,G., Efficace, F., Ciotti,F.,  Roncarolo, M.,  Vacca, A., Piras, E., Littera,R.,  Markous,R.,  Collins,G.,  Ciceri, F., Mandelli,F., Marktel,S& Nasa,G. (2012). Health related quality of life in Middle Eastern children with beta-thalassemia. BMC blood disorders journal, 12 (1),1-6.
Hani, H., Osama, E, & Tamer, H. (2011). Psychological manifestations in adolescents with thalassemia. Middle East Current Psychiatry, 18 (4), 237–244.
Hassan, E., & El Azzab, I. (2016). Study of the health  instructions effect on quality of life and psychological problems among  children with thalassemia. International Journal of Studies in Nursing, 1 (1),16–28.                
Hajbaghery, M., Ahmadi, M& Poormansouri, S. (2015). Health Related Quality of Life, Depression,   in Patients with Beta Thalassemia Major. Iranian Journal of Pediatric Hematology Oncology, 5 (4), 193–205.
Hesham, M., Besher, M. &  Khalifa, N. (2018). Screening for B-Thalassemia Carrier among students in a secondary school in diarb Negm, Sharkia. Zagazig University Medical Journal 24 (1), 72-79.
Higgs, D., Engel, J., & Stamatoyannopoulos, G. (2012). Thalassemia. Lancet, 379 (9813), 373–383.
Hisam, A., Khan, N., Tariq, N., Irfan, H., Arif, B., & Noor, M. (2018). Perceived stress and monetary burden among thalassemia patients and their caregivers. Pakistan Journal of Medical Sciences, 34 (4), 901–906.
Ismail, D., Tagui, M., Hussein, Z.,  Eid, M., & Aly, S. (2018). Evaluation of health-related quality of life and muscular strength in children with beta thalassemia major. Egyptian Journal of Medical Human Genetics, 19 (4), 335- 337.
Johnson, M. (2019). Depression and Anxiety in Thalassemia. Retrieved from https://www.wissh.net/wissh-research/depression-anxiety-thalassemia.
Jain, M., Bagul, A., & Porwal, A. (2013) Psychosocial problems in thalassemic adolescents and young adults. Original Article Journal 4 (1),  21-23.      
Khamoushi, F., Ahmadi, S., Matin, B., Jouybari, T., Alavijeh, M., Mahboubi, M. (2015). Prevalence and socio-demographic characteristics related to stress, anxiety, and depression among patients with major thalassemia in the Kermanshah county. Journal of Biology and Today World, 4 (3), 79-84.
Khoury, B., Musallam, K., Abi-Habib , R. (2012). Prevalence of depression and anxiety in adult patients with β-thalassemia major and intermedia International, Journal of Psychiatry in Medicine, 44 (4), 291-303.
Koutelekos, J., & Haliasos, N. (2013). Depression and thalassemia in children, adolescents and adults. Health Science Journal, 7, 239-246.                 
Lovibond, F., & Lovibond, H. (1995). The structure of negative emotional states: Comparison of the Depression Anxiety Stress Scales (DASS) with the Beck Depression and Anxiety inventories. Behavior, Research and Therapy, 33 (3), 335-343.             
 Maheri, A., Sadeghi,R., Shojaeizadeh, D., Tol,A., Yaseri, M.,& Rohban.,A. (2018). Depression, anxiety, and perceived social support among adults with beta-thalassemia major: Cross-sectional study. Korean Journal Family Medicine, 39 (2),101-107.
Mahmoud, M. (2009). Thalassemia around the World: Egypt. Retrieved       from https://www.thalassemia.org/thalassemia-around-the-world-egypt-2. 
Mohammad, R., Mohammad, P., Ali, D., Morteza, h., Ali, M., Sayed, H., Hossien, F.,  karandish, M.,  Gholamali, H. (2014). The Effect of Partnership Care Model on Anxiety of Adolescent with β-Thalassemia. Jundishapur Journal Chronic Disease Care, 3(4), e23351.
Mohamadia, F., Bagheri, M., Hashemi, M., & Sani, H. (2018). The Effects of Cognitive Behavioral Therapy on Depression and Anxiety among Patients with Thalassemia:  a Randomized Controlled Trial. Journal of Caring Sciences, 7 (4), 219-224.
Nashwan, A., Yassin, M., Babu,G.,  Nair,S.,  Libo,I.,  Hijazi,H.,  Sanctis, V& Soliman., A. (2018). Quality of life among adolescents aged 14 to 18 years with beta-thalassemia major (TM) in Qatar. Acta Biomedica Journal, 89 (2), 16–26.
Patel, P., Beamish, P., Silva, T., Kaushalya, D., Premawardhena, A., & Williams, S. (2019).   Examining depression and quality of life in patients with thalassemia in Sri-Lanka. International Journal of Non-communicable Diseases, 4(1) 27-33.
Punriddum, J., Sanasuttipun, W& Sangperm, P. (2018). Factors Related to Body Image of Adolescents with Thalassemia. Journal Of Nursing Science, 36 (1), 57-72.
Renani, A., Dashtbozorgi, B., Papi, M, Navah, A., & Latifi, M. (                                                      2016).The relation-ship between social capital and self-concept in adolescents with thal-assemia major. Jundishapur Journal Chronic Disease Care, 5, 1-6.
Shafiee, A., Nazar, S., Jorjani, S., Bahraminia, E., & Koupaei, M. (2014). Prevalence of depression in patients with b-thalassemia as assessed by the Beck’s Depression Inventory. Hemoglobin, 38 (4), 289–291.
Smith, Y. (2018). Thalassemia Prevalence. Retrieved from                                               https://www.news-medical.net/health/Thalassemia-Prevalence.aspx.
Vahed, A., Firouzkouhi, M., Mohammad, A & Ghalgaie, J .(2017). Lived experiences of Iranian parents of beta-thalassemia children. Journal of Multidisciplinary Healthcare, 10, 243-251.
Yahia, S., El-Hadidy, A., El-Gilany, H. , Anwar, R., Darwish, A.,& Mansour , K . (2013). Predictor of anxiety and depression in Egyptian  thalassemic  patients: A single center study. International Journal of  Hematology, 97(5), 604- 609.
Yengil, E., Acipayam, C., Kokacya, M., Kurhan, F., Oktay, G& Ozer, C. (2014). Anxiety, depression and quality of life in patients with Beta thalassemia major and their caregivers. International Journal of Clinical and Experimental Medicine, 7 (8), 2165-2172.
Zolaly, M., Zolaly,F., Belowi, L., Shuqdar, R., Belowi Sr, M,.& Alwasaidi,T., Albadrani,M.,(2020). Depression, Anxiety, and Stress Symptoms in Patients with Beta Thalassemia Major in Almadinah Almunawwarah, Saudi Arabia. Cureus Journal, e11367 (11),7-12.