Assessment of Thalassemic Children Knowledge about Thalassemia and Iron Chelation Therapy

Document Type : Original Article

Authors

1 Assist lecturer of pediatric nursing,Faculty of Nursing, Port Said University

2 Assistant Professor of Pediatric Nursing Department, Faculty of Nursing, Port Said University

3 Professor of Pediatric nursing Faculty of Nursing, Port said University

4 Professor of Pediatric Medicine Faculty of Medicine Elazhar University

Abstract

Background: Thalassemia is a major inherited public health problem in the Mediterranean area. Aim of this study was to assess children knowledge about thalassemia and iron chelation therapy. Subjects and methods: A descriptive research design was used. A convenient sample was used; it includes 50 thalassemic children on chelation therapy, and their family caregiver.. This study conducted at the pediatrics outpatient department at the Health Insurance Agency Hospital in Damietta city. Tools Two tools used for data collection. An interview questionnaire form to collect data about socio-demographic characteristics for studied children and their caregivers, assessment of knowledge  related thalassemia and iron chelation therapy  sheet. Results: revealed that, only 26% of children had satisfactory knowledge related thalassemia, and only 12.0% , 26% of the studied children had total satisfactory knowledge related to management of thalassemia and desferal respectively. Conclusion, the study concluded that there is an improvement in the children's knowledge. The study recommended developing frequent educational training programs for children with thalassemia  about chelation therapy through updated posters, booklets and  brochures and a repeat of this research on a large sample and in various places in Egypt for improving children's knowledge and practice

Keywords


Ammad S.A., Mubeen S.M., Shah S.F., and Mansour S. (2011): Parents opinion of Quality of life (QOL) in Pakistan thalassemic children JPMA; 61(5):470-473
Arif F., Fayyaz J., and Hamid A. (2008): Awareness among parent children with Thalassemia major, J. Pak. Med Association; 58(11): 621 – 624
Carman S., and Kyle T. (2015): Nursing care of children with hematologic disorders In: Essential of pediatric nursing, 3rd ed., Philadelphia: Walters Kluwer Health, Lippincott Williams& Wilkins Co., pp. 926
Carman S., and Kyle T. (2015): Nursing care of children with hematologic disorders In: Essential of pediatric nursing, 3rd ed., Philadelphia: Walters Kluwer Health, Lippincott Williams& Wilkins Co., pp. 926
Cooley Anemia Foundation .(2009): What is thalassemia ?Retrived January 23, 2009, from Http://www.thalassemia.org.
El-Awany T.A. (2002): Nutritional program for children with Beta-thalassemia major and their mothers. Unpublished Doctoral Dissertation, Faculty of Nursing, Ain Shams University, Cairo
 El-Beshlawy A. (2008): thalassemic prevalence and status in Egypt. Pediatric research, 40 (5), 760.
Gharagozloo M., Bagherpour B., and Tahanian M. (2009): premature senescence of T Lymphocytes form patient with β-Thalassemia Major. Immunol Lett.;  122(1): 84 – 8.
Hassan E.A. (2010): Impact of educational program on adherence of thalassemia children with iron chelation therapy in hematology clinics. Published Doctoral Dissertation, Faculty of Nursing, Cairo University, Cairo
Khani H., Majdi M.R., Marzabadi E.A., Montazeri A., Ghorbani A., and Ramezani M. (2012): Quality of life of Iranian B-thalassemia Major patients living on the southern coast of the Caspian Sea. Eastern Mediterranean Health Journa;18(4):539-545                                                                                       
Kline N. (2010): Alterations of hematological function in children. pathophysiology: The biologic basis for disease in adults and children  6th ed., Elsevier com. Mosby; P. 999.
Lee Y.L., Lin D.T., and Tsai S.F. (2008): Disease knowledge and treatment adherence among patients with thalassemia major and their mothers in Taiwan. Journal of Clinical Nursing; 18(1):529-538
McCance K. and Grey T. (2010): Altered cellular and tissue biology, 6th ed., Mosby com; P. 952
Mohamed E.M. (2013): Impact of health instruction on improving knowledge and practices of thalassemic adolescents at Zagazig university hospital. Published, Master Thesis, Faculty of Nursing, Zagazig University, Zagazig
Mostafa S., and Abd Elaziz M. (2014): Factors affecting compliance plan of thalassemic children and their mothers in Outpatient Clinic at Zagazig University Hospitals, p. 49
  Origa R. (2017): β-Thalassemia. Genet Med.;19(6):609-619. doi: 10.1038/gim.2016.173. Epub 2016 Nov 3
Satta S., Paglietti M.E., Sollaino M.C., Barella S., Moi P., Desogus M.F., Demartis F.R., Manunza L., and Origa R. (2017): Changes in HbA2 and HbF in alpha thalassemia carriers with KLF1 mutation. Blood Cells Mol Dis.;64:30-32. doi: 10.1016/j.bcmd.2017.03.007. Epub 2017 Mar 18
Wilson D. and Hockenberry M. (2011): Wong's Nursing Care of Infants and Children, 9th ed., Philadelphia Mosby; P. 1439.
Yaish H.M. (2010): Pediatric Thalassemia treatment and management, max j. Coppes HD Phd. Available from: Http://emedicine.medscape.com / article / 958850 – diagnosis
Yaish H.M. (2013): Pediatric Thalassemia. Available at: Http:// emedicine.medscape.com/ article/958850 – overview # show all. Accessed at March 19, 2013.
Yang H.C., Chen Y.C., Mao H.C., and Lin K.H. (2005): Social support and self care behavior in adolescents with beta-thalassemia major. Metabolism; 54(1):15-23.
 Zorac J., Alpern E., Brown L., Loomes K., Marino B., Mollen C. and Raffini J. (2013): Clinical handbook of pediatrics, 5th ed., Philadelphia: Lippincott Williams & Wilkins; P. 431.